Famiglie SMA Onlus was founded in 2001 by a group of Italian parents. Within a few years, it has grown with the help of many other families, and it is now the biggest spinal muscular atrophy charity in Italy. 

Famiglie SMA welcomes and supports new parents. It contributes to the kids' wellness by educating their families and other people who take care of them, and it works to fundraise for the cause. 

The foundation is supported by an Italian Scientific Committee, which includes the best Italina and International experts. Famiglie SMA also collaborates with some of the most renowed hospitals and research centers in Italy. Having so many institutes collaborating helps the foundation find a uniform research standard.

Moreover, Famiglie SMA has developed many partnership with the biggest Italian neuromuscular charities, with whom it has created projects, like the Centri Clinici NeMO in Milano and Messina, and the Numero Verde Stella, both supporting neuromuscular-affected people and the Italian institute Registro per le Malattie Neuromuscolari.